CERTAIN COMORBIDITIES CAN PUT PATIENTS AT RISK FOR SEVERE RSV¹

A prospective, population-based, surveillance study was conducted to estimate the incidence of RSV hospitalization among adults aged ≥18 years overall and those with specific comorbidities. Active and passive surveillance identified 1099 adults hospitalized with RSV in 2 geographical areas (Rochester, NY, and New York City, NY) over 3 RSV seasons (2017-2020). Among the 1039 patients for which detailed demographic data were available, the median age was 69 years; 51% of patients reported a chronic pulmonary condition, and 49% a chronic cardiac condition. The estimated incidence rate ratios (IRRs) were observed among different age groups: 18-49 years, 50-64 years, and ≥65 years from the 2 surveillance areas, with the exception of CHF. The IRRs for CHF included age groups: 20-39 years, 40-59 years, 60-79 years, and ≥80 years. Estimated incidence rates for all comorbid conditions increased with increasing age.²

The IRR for patients aged 18-49 years in the Rochester surveillance area was not statistically significant.²

The estimated IRR for patients aged 18-49 years was only increased in the Rochester surveillance area. There was no increase in risk of RSV hospitalization associated with patients with CAD aged 18-49 years in the New York City surveillance area, as the IRR (95% CI) was 0.87 (0.12-6.33).²

The IRRs for asthma in patients in the Rochester surveillance area were not statistically significant.²